BDBM719005 4-(4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl]piperazin-1-yl)-N-(4-[[(2S)-1,4-dioxan-2-ylmethyl]amino]-3-nitrobenzenesulfonyl)-2-[11-methyl-12-oxo-2,4,10,11-tetraazatricyclo[7.3.0.0{circumflex over ( )}[3,7]]dodeca-1,3(7),5,8-tetraen-10-yl]benzamide::US12220419, Example 70

SMILES Cn1c(=O)c2nc3[nH]ccc3cc2n1-c1ccc(N2CCN(CC3=CCC(C)(C)CC3c3ccc(Cl)cc3)CC2)cc1C(=O)NS(=O)(=O)c1ccc(NC[C@H]2COCCO2)c([N+](=O)[O-])c1

InChI Key InChIKey=HRIDSZULXNJCTB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 719005   

TargetApoptosis regulator Bcl-2(Human)
Newave Pharmaceutical

US Patent
LigandPNGBDBM719005(4-(4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-e...)
Affinity DataIC50: 0.100nMAssay Description:The fluorescence-labeled 23 amino acid peptide BH3 was purchased from CalBiochem (NLWAAQRYGRELRRMSDKFVD). An unbound Fluorescein labeled BH3 peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent