BDBM719091 US20250049780, Example 18

SMILES CO[C@H]1CN[C@@H](C(=O)N2CCC(c3sc4[nH]c(-c5cn6ncnc6c6c5CCC6)c(C(C)C)c4c3C)CC2)C1

InChI Key InChIKey=HJKKYRSDBVUFQV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 719091   

TargetToll-like receptor 7(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719091(US20250049780, Example 18)
Affinity DataEC50:  0.440nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) consist of lymphocytes, monocytes and dendritic cells that express TLR7, TLR8 and TLR9. These cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719091(US20250049780, Example 18)
Affinity DataEC50:  4.42nMAssay Description:Cryopreserved human PBMCs from healthy donors were thawed and resuspended in RPMI-1640 media with L-glutamine (Corning) supplemented with 10% Fetal B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent