BDBM719629 3-chloro-2''-(3-(cyclopropylsulfonyl)-2-fluorophenyl)-3''-fluoro-4-((1S,2S)-2-(5-::US20250051309, Example 6.70

SMILES Cc1cnc(-c2cccc(S(=O)(=O)C3CC3)c2F)c(F)c1-n1c(C)cc([C@H]2C[C@@H]2c2cncc(F)c2)c(Cl)c1=O

InChI Key InChIKey=FQWALNMWAZFEIZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 719629   

TargetMitogen-activated protein kinase 14/1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719629(3-chloro-2'-(3-(cyclopropylsulfonyl)-2-fluoropheny...)
Affinity DataIC50: 0.5nMAssay Description:In a 20 μL reaction, the compounds of various concentrations (20 nL) were pre-incubated with 0.6 nM MK2 (Abcam #ab79910) and 0.06 nM active p38α (Abc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

LigandPNGBDBM719629(3-chloro-2'-(3-(cyclopropylsulfonyl)-2-fluoropheny...)
Affinity DataIC50: 40.4nMAssay Description:In a 10 μL reaction, the compounds of various concentrations (10 nL) were pre-incubated with 3 nM active p38 at (Abcam #ab271606 or in-house prepared...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent