BDBM719701 N-((5-(2-((2-isopropylquinazolin- 4-yl)thio)acetyl)thiophen-2- yl)methyl)pivalamide::US20250051319, Compound 1::US12421222, Compound 1
SMILES CC(C)c1nc(SCC(=O)c2ccc(CNC(=O)C(C)(C)C)s2)c2ccccc2n1
InChI Key InChIKey=KWZVKXCYFVYXQQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 719701
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC enzymes was performed in 384-well plate format using human full-length recombinant HDAC1 and HDAC6, isolated from a baculovirus ex...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Table 9: Inhibition of HDAC enzymes was performed in 384-well plate format using human full-length recombinant HDAC1 and HDAC6, isolated from a bacul...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Table 9: Inhibition of HDAC enzymes was performed in 384-well plate format using human full-length recombinant HDAC1 and HDAC6, isolated from a bacul...More data for this Ligand-Target Pair