BDBM719816 2-hydroxy-N-((5-(2-((6- (trifluoromethyl)oxazolo[4,5- b]pyridin-2- yl)thio)acetyl)thiophen-2- yl)methyl)acetamide::US20250051319, Compound 118::US12421222, Compound 118
SMILES O=C(CO)NCc1ccc(C(=O)CSc2nc3ncc(C(F)(F)F)cc3o2)s1
InChI Key InChIKey=FBZUIFRUEBMHEC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 719816
Affinity DataIC50: 100nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-terminal G...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-terminal G...More data for this Ligand-Target Pair