BDBM719851 2-hydroxy-N-((5-(2-((2- methylpyrido[3,2-d]pyrimidin-4- yl)thio)acetyl)thiophen-2- yl)methyl)acetamide::US20250051319, Compound 153::US12421222, Compound 153

SMILES Cc1nc(SCC(=O)c2ccc(CNC(=O)CO)s2)c2ncccc2n1

InChI Key InChIKey=BDSNICLXSRSYNR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 719851   

TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM719851(2-hydroxy-N-((5-(2-((2- methylpyrido[3,2-d]pyrimid...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM719851(2-hydroxy-N-((5-(2-((2- methylpyrido[3,2-d]pyrimid...)
Affinity DataIC50: 100nMAssay Description:NanoBRET target engagement was performed against the catalytic domain 2 (CD2) of HDAC6, with minor modifications of kit manufacturer protocol (Promeg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM719851(2-hydroxy-N-((5-(2-((2- methylpyrido[3,2-d]pyrimid...)
Affinity DataIC50: 100nMAssay Description:Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-terminal G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent