BDBM720207 preparation of N-methyl-5-(4-((4-methyl-2-oxo-3-(trifluoromethyl)-1,2-dihydro-1,6-naphthyridin-7-yl)methyl)piperazin-1-yl)picolinamide ::US20250051324, Example 2

SMILES CNC(=O)c1ccc(N2CCN(Cc3cc4c(cn3)C(C)=C(C(F)(F)F)C(=O)C4)CC2)cn1

InChI Key InChIKey=RVKIODKELWOUEW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 720207   

TargetPoly [ADP-ribose] polymerase 1(Human)
Keythera (Suzhou) Bio-Pharmaceuticals

US Patent
LigandPNGBDBM720207(preparation of N-methyl-5-(4-((4-methyl-2-oxo-3-(t...)
Affinity DataIC50: 1.22nMAssay Description:The PARP1 assay kit was purchased from BPS Bioscience, USA, specifically the 384-well chemiluminescent assay kit (Catalog No.: #80551).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Keythera (Suzhou) Bio-Pharmaceuticals

US Patent
LigandPNGBDBM720207(preparation of N-methyl-5-(4-((4-methyl-2-oxo-3-(t...)
Affinity DataIC50: 3.14nMAssay Description:The PARP1 assay kit was purchased from BPS Bioscience, USA, specifically the 384-well chemiluminescent assay kit (Catalog No.: #80551).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Keythera (Suzhou) Bio-Pharmaceuticals

US Patent
LigandPNGBDBM720207(preparation of N-methyl-5-(4-((4-methyl-2-oxo-3-(t...)
Affinity DataIC50: 137nMAssay Description:The PARP1 assay kit was purchased from BPS Bioscience, USA, specifically the 384-well chemiluminescent assay kit (Catalog No.: #80551).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent