BDBM720212 preparation of N-methyl-5-(2-methyl-4-((8-methyl-6-oxo-7-(trifluoromethyl)-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)piperazin-1-yl)picolinamide ::US20250051324, Example 10

SMILES CNC(=O)c1ccc(N2CCN(Cc3cnc4c(c3)CC(=O)C(C(F)(F)F)=C4C)CC2C)cn1

InChI Key InChIKey=COFWMMMCLUXKJJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 720212   

TargetPoly [ADP-ribose] polymerase 1(Human)
Keythera (Suzhou) Bio-Pharmaceuticals

US Patent
LigandPNGBDBM720212(preparation of N-methyl-5-(2-methyl-4-((8-methyl-6...)
Affinity DataIC50: 2.79nMAssay Description:The PARP1 assay kit was purchased from BPS Bioscience, USA, specifically the 384-well chemiluminescent assay kit (Catalog No.: #80551).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent