BDBM720225 preparation of N-methyl-1''-((4-methyl-2-oxo-3-(trifluoromethyl)-1,2-dihydro-1,6-naphthyridin-7-yl)methyl)-1'',2'',3'',6''-tetrahydro-[3,4''-bipyridine]-6-carboxamide (::US20250051324, Example 89

SMILES CNC(=O)c1ccc(C2=CCN(Cc3cc4c(cn3)C(C)=C(C(F)(F)F)C(=O)C4)CC2)cn1

InChI Key InChIKey=ABYCTZWMVUEPFJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 720225   

TargetPoly [ADP-ribose] polymerase 1(Human)
Keythera (Suzhou) Bio-Pharmaceuticals

US Patent
LigandPNGBDBM720225(preparation of N-methyl-1'-((4-methyl-2-oxo-3-(tri...)
Affinity DataIC50: 1.53nMAssay Description:The PARP1 assay kit was purchased from BPS Bioscience, USA, specifically the 384-well chemiluminescent assay kit (Catalog No.: #80551).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent