BDBM720229 preparation of N-cyclopropyl-5-(4-((8-methyl-6-oxo-7-(trifluoromethyl)-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)piperazin-1-yl)picolinamide (::US20250051324, Example 99

SMILES Cc1c(C(F)(F)F)c(=O)[nH]c2cc(CN3CCN(c4ccc(C(=O)NC5CC5)nc4)CC3)cnc12

InChI Key InChIKey=BDNQEZXCWBOODK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 720229   

TargetPoly [ADP-ribose] polymerase 1(Human)
Keythera (Suzhou) Bio-Pharmaceuticals

US Patent
LigandPNGBDBM720229(preparation of N-cyclopropyl-5-(4-((8-methyl-6-oxo...)
Affinity DataIC50: 1.53nMAssay Description:The PARP1 assay kit was purchased from BPS Bioscience, USA, specifically the 384-well chemiluminescent assay kit (Catalog No.: #80551).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent