BDBM720685 (R)-3-methyl-4-(2-(6-methyl-1H-indol-4-yl)-7-(methylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)morpholine ::US20250051362, Compound 29::US12435095, Compound 29

SMILES Cc1cc(-c2cc3c(ccn3S(C)(=O)=O)c(N3CCOC[C@H]3C)n2)c2cc[nH]c2c1

InChI Key InChIKey=BGQDWJSDEYQDRW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 720685   

TargetSerine/threonine-protein kinase ATR(Human)
Shanghai Annova Biotechnology Co.

US Patent
LigandPNGBDBM720685((R)-3-methyl-4-(2-(6-methyl-1H-indol-4-yl)-7-(meth...)
Affinity DataIC50: 2.30nMAssay Description:Experimental method: The inhibitory activity of the compounds on ATR kinase in vitro was determined by Mobility Shift Assay at an ATP concentration o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Shanghai Annova Biotechnology Co.

US Patent
LigandPNGBDBM720685((R)-3-methyl-4-(2-(6-methyl-1H-indol-4-yl)-7-(meth...)
Affinity DataIC50: 2.30nMAssay Description:The inhibitory activity of the compounds on ATR kinase in vitro was determined by Mobility Shift Assay at an ATP concentration of Km using Caliper EZ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent