BDBM720921 (1''S,4''S)-6''-bromo-8-(difluoromethoxy)-3'',3'',5''-trifluoro-6-(trifluoromethyl)-3'',4''-dihydro-2''H,3H-spiro[imidazo[1,2-a]pyridine-2,1''-naphthalen]-4''-ol and (1''S,4''R)-6''-bromo-8-(difluoromethoxy)-3'',3'',5''-trifluoro-6-(trifluoromethyl)-3'',4''-dihydro-2''H,3H-spiro[imidazo[1,2-a]pyridine-2,1''-naphthalen]-4''-ol::US12226405, Example 18

SMILES O[C@@H]1c2c(ccc(Br)c2F)[C@]2(CN3C=C(C(F)(F)F)C=C(OC(F)F)C3=N2)CC1(F)F

InChI Key InChIKey=GZBRKGJJPKRVQS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 720921   

TargetEndothelial PAS domain-containing protein 1(Human)
Novartis

US Patent
LigandPNGBDBM720921((1'S,4'S)-6'-bromo-8-(difluoromethoxy)-3',3',5'-tr...)
Affinity DataIC50: 6nMAssay Description:The scintillation proximal assay (SPA) was based on a competition binding assay with the radio-ligand N-(3-chloro-5-fluorophenyl-4-t)-4-nitrobenzo[c]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
6/17/2025
Entry Details
US Patent