BDBM721041 8-(6-(3-((dimethylamino)methyl)pyrrolidin-1-yl)pyridin-3-yl)-7-fluoro-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]cinnolin-2(3H)-one::US12226414, Example 21

SMILES CN(C)CC1CCN(c2ccc(-c3cc4c(cc3F)nnc3c4n(C4CCOCC4)c(=O)n3C)cn2)C1

InChI Key InChIKey=ZQXIUTZVPAVMJX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721041   

TargetSerine-protein kinase ATM(Human)
Suzhou Zanrong Pharma

US Patent
LigandPNGBDBM721041(8-(6-(3-((dimethylamino)methyl)pyrrolidin-1-yl)pyr...)
Affinity DataIC50: 97nMAssay Description:ATM (Millipore, Cat. No. 14-933) enzyme solution was prepared in 1× kinase base buffer. 10 μl of 2× enzyme solution was transferred to each well of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent