BDBM721115 (+)-N-[4-(3-anilino-5-methyl-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl)pyridin-2-yl]-2-(pyridin-4-yl)propanamide (Enantiomer 1)::US12227501, Example 73

SMILES CC(C(=O)Nc1cc(-c2[nH]c3c(c2Nc2ccccc2)C(=O)N(C)CC3)ccn1)c1ccncc1

InChI Key InChIKey=VZLYECDBMSJTQG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 721115   

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM721115((+)-N-[4-(3-anilino-5-methyl-4-oxo-4,5,6,7-tetrahy...)
Affinity DataIC50: 2.38nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a white 1536-well microtiter plate (Greiner Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM721115((+)-N-[4-(3-anilino-5-methyl-4-oxo-4,5,6,7-tetrahy...)
Affinity DataIC50: 4.46nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a white 1536-well microtiter plate (Greiner Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM721115((+)-N-[4-(3-anilino-5-methyl-4-oxo-4,5,6,7-tetrahy...)
Affinity DataIC50: 63.3nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a white low volume 384-well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [669-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM721115((+)-N-[4-(3-anilino-5-methyl-4-oxo-4,5,6,7-tetrahy...)
Affinity DataIC50: 6.78E+3nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent