BDBM721227 US12227502, Example 21

SMILES CC(C)C4Oc1c(cc([N+](=O)[O-])cc1c2cn(C)c(=O)c3[nH]ccc23)NC4=O

InChI Key InChIKey=BJFXRUBKKJTYMK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 721227   

TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent
LigandPNGBDBM721227(US12227502, Example 21)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhibitors were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Incyte

US Patent
LigandPNGBDBM721227(US12227502, Example 21)
Affinity DataIC50: 550nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhibitors were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent