BDBM721233 US12227502, Example 25

SMILES COc5cc2NC(=O)C(c1ccc(F)cc1Cl)Oc2c(c3cn(C)c(=O)c4[nH]ccc34)c5

InChI Key InChIKey=NNJNYMIRXGUCJK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 721233   

TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent
LigandPNGBDBM721233(US12227502, Example 25)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhibitors were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Incyte

US Patent
LigandPNGBDBM721233(US12227502, Example 25)
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhibitors were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent