BDBM721538 methyl (E)-4-(2-(2-(N-(1-(1-(naphthalen-1-yl)ethyl)piperidin-4-yl)propionamido)acetamido)acetamido)but-2-enoate::US20250059159, Compound 15

SMILES CCC(=O)N(CC(=O)NCC(=O)NC/C=C/C(=O)OC)C1CCN(C(C)c2cccc3ccccc23)CC1

InChI Key InChIKey=KDJYOLMZABKGAG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 721538   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shanghai Synergy Pharmaceutical Sciences

US Patent
LigandPNGBDBM721538(methyl (E)-4-(2-(2-(N-(1-(1-(naphthalen-1-yl)ethyl...)
Affinity DataIC50: 100nMAssay Description:The PLpro enzyme was purified as described above and prepared in assay buffer (50 mM HEPES, pH 7.5, 0.01% Triton X-100 (v/v), 0.1 mg mL-1 BSA, and 2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent