BDBM72179 MLS000583247::N-[3,5-dimethyl-1-(2-methylbenzyl)-1H-pyrazol-4-yl]-9H-xanthene-9-carboxamide::N-[3,5-dimethyl-1-(2-methylbenzyl)pyrazol-4-yl]-9H-xanthene-9-carboxamide::N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]-4-pyrazolyl]-9H-xanthene-9-carboxamide::N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-9H-xanthene-9-carboxamide::SMR000201083::cid_1245690

SMILES Cc1nn(Cc2ccccc2C)c(C)c1NC(=O)C1c2ccccc2Oc2ccccc12

InChI Key InChIKey=VHJMGTGIAIDRTE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72179   

TargetGTPase KRas [1-169,G12C](Human)
SchroDinger

US Patent
LigandChemical structure of BindingDB Monomer ID 72179BDBM72179(US20250368634, Example 14)
Affinity DataIC50: 21.7nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
Target InfoKEGG
GoogleScholar
In Depth
Date in BDB:
4/15/2026
Entry Details US Patent