BDBM722402 US20250059185, Example 4

SMILES COc1cccc(C(=O)N2CCc3c(nn(C)c3-c3cc(Cl)cc(S(N)(=O)=O)c3)[C@@H]2C)c1Cl

InChI Key InChIKey=HUIZGTGZCKKPTK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 722402   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM722402(US20250059185, Example 4)
Affinity DataIC50: 27nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent