BDBM722454 US20250059185, Example 56

SMILES C=S(N)(=O)c1cc(Cl)cc(-c2c3c(nn2C)C(C)N(C(=O)c2cc(F)cc(-c4ccc(=O)[nH]c4)c2Cl)CC3)c1

InChI Key InChIKey=IRKKSIYUYKKUIQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 722454   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM722454(US20250059185, Example 56)
Affinity DataIC50: 12nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent