BDBM722468 US20250059185, Example 70

SMILES CC1c2nn(C)c(-c3cc(Cl)cc(C4(C(N)=O)CC4)c3)c2CCN1C(=O)c1cc(F)cc(OCC2CNC(=O)C2)c1Cl

InChI Key InChIKey=WZIOHKRJGAFJGT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 722468   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM722468(US20250059185, Example 70)
Affinity DataIC50: 42nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent