BDBM722496 US20250059185, Example 98

SMILES C[C@H]1C2NN(C)C(c3cc(F)cc(F)c3)=C2CCN1C(=O)c1cc(F)cc(C2=CC(Cl)C(=O)N=C2)c1Cl

InChI Key InChIKey=ZJTWSDWCGXZYIL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 722496   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM722496(US20250059185, Example 98)
Affinity DataIC50: 5.97nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent