BDBM722498 US20250059185, Example 100

SMILES C[C@H]1C2NN(C)C(c3cc(F)cc(F)c3)=C2CCN1C(=O)c1ncn(C2=CC(Cl)CN=C2O)n1

InChI Key InChIKey=TZZFWWZHSHCOLZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 722498   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM722498(US20250059185, Example 100)
Affinity DataIC50: 31.9nMAssay Description:MAGL inhibitory activity by determining the enzymatic activity by following the hydrolysis of the natural substrate 2-arachidonoylglycerol (2-AG) res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent