BDBM722548 (S)-N-(4- (4-amino- 7-(pyridin-4- yl)pyrazolo [1,5-a] pyrazin-3- yl)-2-(1- (4-fluorophenyl) ethoxy)phenyl)- 1,1- difluoromethane- sulfonamide::US20250059188, Compound 39::US20250115598, Compound 39
SMILES C[C@H](Oc1cc(-c2cnn3c(-c4ccncc4)cnc(N)c23)ccc1NS(=O)(=O)C(F)F)c1ccc(F)cc1
InChI Key InChIKey=IRBLLVQXZMTMNP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 722548
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: <50nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair