BDBM722608 (S)-N-(4-(4- amino-1-methyl- 7-(1-(2- methyl-2-azaspiro [3.3]heptan-6-yl)- 1H-pyrazol-4-yl)- 1H-pyrazolo[4,3- c]pyridin-3-yl)- 2-(1-(4- fluorophenyl)ethoxy) phenyl)-1,1- difluoromethane- sulfonamide::US20250059188, Compound 99

SMILES CNc1c(-c2cnn(C3CC4(C3)CN(C)C4)c2)cnc(N)c1C(=N)c1ccc(NS(=O)(=O)C(F)F)c(O[C@@H](C)c2ccc(F)cc2)c1

InChI Key InChIKey=NVIDQONPNRSFPY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 722608   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722608((S)-N-(4-(4- amino-1-methyl- 7-(1-(2- methyl-2-aza...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722608((S)-N-(4-(4- amino-1-methyl- 7-(1-(2- methyl-2-aza...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722608((S)-N-(4-(4- amino-1-methyl- 7-(1-(2- methyl-2-aza...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent