BDBM722616 (S)-N-(4-(4-amino-1-methyl-7- (6-(4-methylpiperazin-1- yl)pyridin-3-yl)-1H-pyrazolo[4,3- c]pyridin-3-yl)-2-(1-(4- fluorophenyl)ethoxy)phenyl)- 1,1-difluoromethanesulfonamide::US20250059188, Compound 107

SMILES C[C@@H](Oc1cc(-c2nn(C)c3c(-c4ccc(N5CCN(C)CC5)nc4)cnc(N)c23)ccc1NS(=O)(=O)C(F)F)c1ccc(F)cc1

InChI Key InChIKey=AUPWZRSXDPOGRQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 722616   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722616((S)-N-(4-(4-amino-1-methyl-7- (6-(4-methylpiperazi...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722616((S)-N-(4-(4-amino-1-methyl-7- (6-(4-methylpiperazi...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722616((S)-N-(4-(4-amino-1-methyl-7- (6-(4-methylpiperazi...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent