BDBM722638 (S)-N-(4-(4-amino-1- methyl-7-(1- (tetrahydro-2H-pyran- 4-yl)-1H-pyrazol-4-yl)- 1H-pyrazolo[4,3- c]pyridin-3-yl)-2-(1-(4- methoxyphenyl)ethoxy) phenyl)-1,1- difluoromethane- sulfonamide::US20250059188, Compound 129::US20250115598, Compound 129
SMILES COc1ccc([C@H](C)Oc2cc(-c3nn(C)c4c(-c5cnn(C6CCOCC6)c5)cnc(N)c34)ccc2NS(=O)(=O)C(F)F)cc1
InChI Key InChIKey=UZASFWJJTRMJIM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 722638
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: <50nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair