BDBM722664 N-(4-(4-amino- 1-methyl-7-(1- (1,2,2- trimethylpiperidin- 4-yl)-1H-pyrazol- 4-yl)-1H- pyrazolo[4,3-c] pyridin-3-yl)- 2-((S)-1-(4- chlorophenyl) ethoxy) phenyl)-1,1- difluoromethane- sulfonamide::US20250059188, Compound 159::US20250115598, Compound 159
SMILES C[C@H](Oc1cc(-c2nn(C)c3c(-c4cnn(C5CCN(C)C(C)(C)C5)c4)cnc(N)c23)ccc1NS(=O)(=O)C(F)F)c1ccc(Cl)cc1
InChI Key InChIKey=LAPQLPWVDHWYHI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 722664
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: <50nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair