BDBM722665 (S)-N-(4-(4-amino-1-methyl-7- (3-methyl-2-oxo-2,3-dihydro- 1H-benzo[d]imidazol-5-yl)-1H- pyrazolo[4,3-c]pyridin-3-yl)-2-(1-(4- fluorophenyl)ethoxy)phenyl)-1,1- difluoromethanesulfonamide::US20250059188, Compound 160::US20250115598, Compound 160
SMILES C[C@H](Oc1cc(-c2nn(C)c3c(-c4ccc5[nH]c(=O)n(C)c5c4)cnc(N)c23)ccc1NS(=O)(=O)C(F)F)c1ccc(F)cc1
InChI Key InChIKey=GWEJKOBCRLOGAB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 722665
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: <50nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair