BDBM722669 N-(4-(4-amino- 1-methyl-7-(1- ((3aR,6aS)-2- methyloctahydro- cyclopenta[c]pyrrol- 5-yl)-1H-pyrazol- 4-yl)-1H- pyrazolo[4,3-c] pyridin- 3-yl)-2-((S)-1- (4-fluorophenyl) ethoxy)phenyl)-1,1- difluoromethane- sulfonamide::US20250059188, Compound 164::US20250115598, Compound 164
SMILES C[C@H](Oc1cc(-c2nn(C)c3c(-c4cnn(C5C[C@@H]6CN(C)C[C@@H]6C5)c4)cnc(N)c23)ccc1NS(=O)(=O)C(F)F)c1ccc(F)cc1
InChI Key InChIKey=TYAVYXCZBIKGBL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 722669
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: <50nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >2.50E+3nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair