BDBM72311 2,8-Difluoro-3-(trifluoromethyl)-10,11,12,13-tetrahydro-19H-5,18-methanodibenzo[f,i]pyrido[2,3,-b][1,4,8]triazacyclotridecine-15,19(14H)-dione::US20250368647, Example 32

SMILES O=C1c2cc(F)c(C(F)(F)F)cc2N2CN1c1ccc(=O)[nH]c1NCCCc1cc(F)ccc12

InChI Key InChIKey=PIWYCUMSWNQTQW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72311   

TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandChemical structure of BindingDB Monomer ID 72311BDBM72311(2,8-Difluoro-3-(trifluoromethyl)-10,11,12,13-tetra...)
Affinity DataIC50: 3.98nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2026
Entry Details
US Patent