BDBM723310 US20250059220, Compound 422

SMILES CNC(=O)c1cc(OCCCS(C)(=O)=O)c2sc(C(F)(F)P(=O)(O)O)c(C#N)c2c1

InChI Key InChIKey=VFRGJCJXWUENFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 723310   

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM723310(US20250059220, Compound 422)
Affinity DataIC50: 7.84nMAssay Description:Test compounds were dissolved in DMSO, and 10-point serial 3-fold dilution series in DMSO were prepared in Echo Qualified 384-well Polypropylene Micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM723310(US20250059220, Compound 422)
Affinity DataIC50: 11.7nMAssay Description:Test compounds were dissolved in DMSO, and 10-point serial 3-fold dilution series in DMSO were prepared in Echo Qualified 384-well Polypropylene Micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent