BDBM723331 US20250059220, Compound 443

SMILES Cc1c(C(F)(F)P(=O)(O)O)sc2c(OCCCS(N)(=O)=O)cc(-c3nc[nH]n3)cc12

InChI Key InChIKey=SPHDXLHQZXGWHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 723331   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM723331(US20250059220, Compound 443)
Affinity DataIC50: 5.10nMAssay Description:Test compounds were dissolved in DMSO, and 10-point serial 3-fold dilution series in DMSO were prepared in Echo Qualified 384-well Polypropylene Micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM723331(US20250059220, Compound 443)
Affinity DataIC50: 6.17nMAssay Description:Test compounds were dissolved in DMSO, and 10-point serial 3-fold dilution series in DMSO were prepared in Echo Qualified 384-well Polypropylene Micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent