BDBM723353 (1-(2,6-Bis-methylamino-8-propylamino-pyrimido[5,4-d]pyrimidin-4-yl amino)-2-methyl-propan-2-ol)::US20250057848, Compound GAL-475

SMILES CCCNc1nc(NC)nc2c1NC(NC)N=C2NCC(C)(C)O

InChI Key InChIKey=QBSPRJZXXDLFNL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 723353   

TargetNeurotensin receptor type 1(Human)
Neurim Pharmaceuticals (1991)

US Patent
LigandPNGBDBM723353((1-(2,6-Bis-methylamino-8-propylamino-pyrimido[5,4...)
Affinity DataEC50:  355nMAssay Description:Inhibition higher than 50% of a certain receptor radioligand in the presence of 30 micromolar GAL475 was observed with 5-HT2B(h) (agonist radioligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent