BDBM723372 (6-(4-fluoro-1H-pyrazol- 1-yl)pyridin-3-yl)(7-(4- methyl-6-((5-methyl-1H- pyrazol-3-yl)amino)pyrimidin- 2-yl)-3-oxa-7,9-diazabicyclo [3.3.1]nonane- 9-yl)methanone::US12234222, Compound I-7

SMILES Cc1cc(Nc2cc(C)[nH]n2)nc(N2CC3COCC(C2)N3C(=O)c2ccc(-n3cc(F)cn3)nc2)n1

InChI Key InChIKey=SZTLWJSWANAPBP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 723372   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM723372((6-(4-fluoro-1H-pyrazol- 1-yl)pyridin-3-yl)(7-(4-...)
Affinity DataIC50: 10.3nMAssay Description:The experimental steps are as follows:(1) The test compound (the compound of the present disclosure, and compound 164 in WO2018017983A1 as a control)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM723372((6-(4-fluoro-1H-pyrazol- 1-yl)pyridin-3-yl)(7-(4-...)
Affinity DataIC50: 391nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
US Patent