BDBM723375 (6-(6,6-dimethyl-3-azabicyclo [3.1.0]hexane-3-yl) pyridin-3-yl)(3-(4-methyl- 6-((5-methyl-1H-pyrazol- 3-yl)amino)pyrimidin-2- yl)-3,8-diazabicyclo[3.2.1] octane-8-yl)methanone::US12234222, Compound I-10

SMILES Cc1cc(Nc2cc(C)[nH]n2)nc(N2CC3CCC(C2)N3C(=O)c2ccc(N3CC4C(C3)C4(C)C)nc2)n1

InChI Key InChIKey=MOMLVEYENYRVHJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 723375   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM723375((6-(6,6-dimethyl-3-azabicyclo [3.1.0]hexane-3-yl)...)
Affinity DataIC50: 7.30nMAssay Description:The experimental steps are as follows:(1) The test compound (the compound of the present disclosure, and compound 164 in WO2018017983A1 as a control)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM723375((6-(6,6-dimethyl-3-azabicyclo [3.1.0]hexane-3-yl)...)
Affinity DataIC50: 1.55E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
US Patent