BDBM723382 (6-(4-fluoro-1H-pyrazol- 1-yl)pyridin-3-yl)(3-(4- (hydroxymethyl)- 6-((5-methyl- 1H-pyrazol-3-yl)amino) pyrimidin-2-yl)-3,8- diazabicyclo[3.2.1]octane- 8-yl)methanone::US12234222, Compound I-20

SMILES Cc1cc(Nc2cc(CO)nc(N3CC4CCC(C3)N4C(=O)c3ccc(-n4cc(F)cn4)nc3)n2)n[nH]1

InChI Key InChIKey=CCUUDEMWQBBGBT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 723382   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM723382((6-(4-fluoro-1H-pyrazol- 1-yl)pyridin-3-yl)(3-(4-...)
Affinity DataIC50: 3nMAssay Description:The experimental steps are as follows:(1) The test compound (the compound of the present disclosure, and compound 164 in WO2018017983A1 as a control)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM723382((6-(4-fluoro-1H-pyrazol- 1-yl)pyridin-3-yl)(3-(4-...)
Affinity DataIC50: 1.55E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
US Patent