BDBM723385 (6-(4-fluorophenyl)pyridin- 3-yl)(3-(4-methyl-6-((5- methyl-1H-pyrazol-3-yl) amino)pyrimidin-2-yl)-3, 8-diazabicyclo[3.2.1]octane 8-yl)methanone::US12234222, Compound I-25

SMILES Cc1cc(Nc2cc(C)[nH]n2)nc(N2CC3CCC(C2)N3C(=O)c2ccc(-c3ccc(F)cc3)nc2)n1

InChI Key InChIKey=SQXGUVZOXXNPJG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 723385   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM723385((6-(4-fluorophenyl)pyridin- 3-yl)(3-(4-methyl-6-(...)
Affinity DataIC50: 5.60nMAssay Description:The experimental steps are as follows:(1) The test compound (the compound of the present disclosure, and compound 164 in WO2018017983A1 as a control)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM723385((6-(4-fluorophenyl)pyridin- 3-yl)(3-(4-methyl-6-(...)
Affinity DataIC50: 260nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
US Patent