BDBM724098 Step 1: 2-(Methoxycarbamoyl)-5-methylthiophene-3-carboxylic acid (17a-1) and 3-(methoxy-carbamoyl)-5-methylthiophene-2-carboxylic acid (17a-2)::US20250066290, Example 17-1

SMILES [2H]C([2H])([2H])Oc3cccc(c2c(F)c(F)c(NC(=O)c1ncsc1C(=O)NOC)c(F)c2F)c3

InChI Key InChIKey=IUNRCIRKOZNHIK-FIBGUPNXSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724098   

LigandPNGBDBM724098(Step 1: 2-(Methoxycarbamoyl)-5-methylthiophene-3-c...)
Affinity DataIC50: 100nMAssay Description:The in vitro inhibition of hDHODH was measured using an N-terminally truncated recombinant hDHODH enzyme as described in J. Med. Chem. 2006; 49:1239....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
6/29/2025
Entry Details
US Patent