BDBM724200 US20250066318, Compound II.2

SMILES Cn1cc(C(=O)Nc2ncc(-c3ccc(C#N)cc3)s2)ccc1=O

InChI Key InChIKey=KXQNLTYLMNPHNJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724200   

LigandChemical structure of BindingDB Monomer ID 724200BDBM724200(US20250066318, Compound II.2)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at estrogen receptor alpha (unknown origin) assessed as inhibition of estradiol-induced response after 22 hrs by cell-based lucif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 724200BDBM724200(US20250066318, Compound II.2)
Affinity DataIC50: 100nMAssay Description:1. Add 5 μL enzyme & substrate mixture to each well in Column 2-23 and A24-H24 wells of the 384-well assay plate;2. Add 5 μL 0% Phosphorylation contr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/1/2025
Entry Details
US Patent