BDBM72430 5-(1,2-dihydroxyethyl)-6-hydroxytetrahydrofuro[2,3-d][1,3]oxazole-2(3H)-thione::5-[(1R)-1,2-bis(oxidanyl)ethyl]-6-oxidanyl-3a,5,6,6a-tetrahydro-3H-furo[2,3-d][1,3]oxazole-2-thione::5-[(1R)-1,2-dihydroxyethyl]-6-hydroxy-3a,5,6,6a-tetrahydro-3H-furo[2,3-d][1,3]oxazole-2-thione::5-[(1R)-1,2-dihydroxyethyl]-6-hydroxy-3a,5,6,6a-tetrahydro-3H-furo[2,3-d]oxazole-2-thione::MLS000701848::SMR000226772::cid_16189303

SMILES OC[C@@H](O)C1OC2NC(=S)OC2C1O

InChI Key InChIKey=PKBVCSNCOXHULL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 72430   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandChemical structure of BindingDB Monomer ID 72430BDBM72430(N-(2-fluoro-5-(6-(6-methylpyridin-2- yl)-2,3-dihyd...)
Affinity DataKi: <1nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details PCBioAssay
TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandChemical structure of BindingDB Monomer ID 72430BDBM72430(N-(2-fluoro-5-(6-(6-methylpyridin-2- yl)-2,3-dihyd...)
Affinity DataIC50: 1nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details PCBioAssay