BDBM724579 8-bromo-2-(morpholin-4-yl)-N-({5-[4-(trifluoromethoxy)phenyl]-4H-1,2,4-triazol-3-yl}methyl)pyrazolo[1,5-a][1,3,5]triazin-4-amine::US20250066370, Example 2

SMILES FC(F)(F)Oc1ccc(-c2nnc(CNc3nc(N4CCOCC4)nc4c(Br)cnn34)[nH]2)cc1

InChI Key InChIKey=MRJAZDMHCUHEPU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 724579   

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Deutsches Krebsforschungszentrum

US Patent
LigandPNGBDBM724579(8-bromo-2-(morpholin-4-yl)-N-({5-[4-(trifluorometh...)
Affinity DataIC50: 750nMAssay Description:For the assay 50 nanoL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Deutsches Krebsforschungszentrum

US Patent
LigandPNGBDBM724579(8-bromo-2-(morpholin-4-yl)-N-({5-[4-(trifluorometh...)
Affinity DataIC50: 6.35E+3nMAssay Description:For the assay 50 nanoL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Deutsches Krebsforschungszentrum

US Patent
LigandPNGBDBM724579(8-bromo-2-(morpholin-4-yl)-N-({5-[4-(trifluorometh...)
Affinity DataIC50: 1.12E+4nMAssay Description:For the assay 50 nanoL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent