BDBM724601 N-{[5-(6-methoxypyridin-3-yl)-1H-imidazol-2-yl]methyl}-2-(morpholin-4-yl)-8-(trifluoromethyl)pyrazolo[1,5-a][1,3,5]triazin-4-amine::US20250066370, Example 21

SMILES COc1ccc(-c2cnc(CNc3nc(N4CCOCC4)nc4c(C(F)(F)F)cnn34)[nH]2)cn1

InChI Key InChIKey=PDQHJJNMENWTCQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724601   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Deutsches Krebsforschungszentrum

US Patent
LigandPNGBDBM724601(N-{[5-(6-methoxypyridin-3-yl)-1H-imidazol-2-yl]met...)
Affinity DataIC50: 3.05E+3nMAssay Description:For the assay 50 nanoL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Deutsches Krebsforschungszentrum

US Patent
LigandPNGBDBM724601(N-{[5-(6-methoxypyridin-3-yl)-1H-imidazol-2-yl]met...)
Affinity DataIC50: 6.39E+3nMAssay Description:For the assay 50 nanoL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent