BDBM725016 US12240835, Example 43

SMILES O=C(Nc1ccc(OC(F)(F)Cl)cc1)C1C=C(C2C=NC=NC2)c2c(nc3n2C[C@@H](O)CC3)C1

InChI Key InChIKey=JKQXKGYDLDAZCA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 725016   

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM725016(US12240835, Example 43)
Affinity DataIC50: 0.380nMAssay Description:ABL1 WT protein (64-515aa) containing an N-terminal His tag was produced by co-expression with YopH in Sf9 insect cells. Cells were harvested by cent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/6/2025
Entry Details
US Patent