BDBM725111 Cis-(P)-1-(5-Fluoro-2-Methoxy-4-(3-(Trifluoromethyl)Cyclobutyl)Phenyl)-N-(Isoxazol-3-Yl)-2-Oxo-1,2-Dihydroquinoline-6-Sulfonamide and Trans-(P)-1-(5-Fluoro-2-Methoxy-4-(3-(Trifluoromethyl)Cyclobutyl)Phenyl)-N-(Isoxazol-3-Yl)-2-Oxo-1,2-Dihydroquinoline-6-Sulfonamide, Respectively::US12240839, Example 6

SMILES COc1cc([C@H]2C[C@@H](C(F)(F)F)C2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21

InChI Key InChIKey=PKROBNQQUVPRER-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 725111   

LigandPNGBDBM725111(Cis-(P)-1-(5-Fluoro-2-Methoxy-4-(3-(Trifluoromethy...)
Affinity DataIC50: 11nMAssay Description:Human Nav1.7 currents were recorded in population patch-clamp mode with the IWB automated electrophysiology system (Molecular Devices, LLC, Sunnyvale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
7/6/2025
Entry Details
US Patent