BDBM725121 Cis-(P)-1-(5-Chloro-2-Methoxy-4-(3-(Trifluoromethyl)Cyclobutyl)Phenyl)-2-Oxo-N-(Pyrimidin-2-Yl)-1,2-Dihydroquinoline-6-Sulfonamide and Trans-(P)-1-(5-Chloro-2-Methoxy-4-(3-(Trifluoromethyl)Cyclobutyl)Phenyl)-2-Oxo-N-(Pyrimidin-2-Yl)-1,2-Dihydroquinoline-6-Sulfonamide, Respectively::US12240839, Example 16

SMILES COc1cc([C@H]2C[C@H](C(F)(F)F)C2)c(Cl)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ncccn3)ccc21

InChI Key InChIKey=BCEMMHZEZDECRV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 725121   

LigandPNGBDBM725121(Cis-(P)-1-(5-Chloro-2-Methoxy-4-(3-(Trifluoromethy...)
Affinity DataIC50: 18nMAssay Description:Human Nav1.7 currents were recorded in population patch-clamp mode with the IWB automated electrophysiology system (Molecular Devices, LLC, Sunnyvale...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/6/2025
Entry Details
US Patent