BDBM725320 3-(4-(((4- chlorophenyl) methyl)sulfonamido) phenyl)-5- (pyrazin-2- ylamino)-1H- pyrazole-4- carboxamide::US20250074891, Compound 70::US12583836, Compound 70

SMILES NC(=O)c1c(-c2ccc(NS(=O)(=O)Cc3ccc(Cl)cc3)cc2)n[nH]c1Nc1cnccn1

InChI Key InChIKey=LXTQRNRRYYUTJN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 725320   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725320BDBM725320(3-(4-(((4- chlorophenyl) methyl)sulfonamido) pheny...)
Affinity DataKd: <10nMAssay Description:In this reporter gene cell based ALK2 and TGFβ assay, the C2Cl2 cell line was employed for the measurement of ALK2 activity, using a BRE-Luc SMA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725320BDBM725320(3-(4-(((4- chlorophenyl) methyl)sulfonamido) pheny...)
Affinity DataKd: <10nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725320BDBM725320(3-(4-(((4- chlorophenyl) methyl)sulfonamido) pheny...)
Affinity DataKd: >3.00E+4nMAssay Description:In this reporter gene cell based ALK2 and TGFβ assay, the C2Cl2 cell line was employed for the measurement of ALK2 activity, using a BRE-Luc SMA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725320BDBM725320(3-(4-(((4- chlorophenyl) methyl)sulfonamido) pheny...)
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725320BDBM725320(3-(4-(((4- chlorophenyl) methyl)sulfonamido) pheny...)
Affinity DataKd: >3.00E+4nMAssay Description:In this reporter gene cell based ALK2 and TGFβ assay, the C2Cl2 cell line was employed for the measurement of ALK2 activity, using a BRE-Luc SMA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725320BDBM725320(3-(4-(((4- chlorophenyl) methyl)sulfonamido) pheny...)
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent