BDBM725402 3-(4-(ethylsulfonamido)-3-(1- phenylcyclopropoxy)phenyl)-5- (pyrazin-2-ylamino)-1H-pyrazole-4- carboxamide::US20250074891, Compound 152::US12583836, Compound 152

SMILES CCS(=O)(=O)Nc1ccc(-c2n[nH]c(Nc3cnccn3)c2C(N)=O)cc1OC1(c2ccccc2)CC1

InChI Key InChIKey=IASANLBKRJMLLL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 725402   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725402BDBM725402(3-(4-(ethylsulfonamido)-3-(1- phenylcyclopropoxy)p...)
Affinity DataKd: <10nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725402BDBM725402(3-(4-(ethylsulfonamido)-3-(1- phenylcyclopropoxy)p...)
Affinity DataKd: <10nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725402BDBM725402(3-(4-(ethylsulfonamido)-3-(1- phenylcyclopropoxy)p...)
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725402BDBM725402(3-(4-(ethylsulfonamido)-3-(1- phenylcyclopropoxy)p...)
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725402BDBM725402(3-(4-(ethylsulfonamido)-3-(1- phenylcyclopropoxy)p...)
Affinity DataKd: >3.00E+4nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725402BDBM725402(3-(4-(ethylsulfonamido)-3-(1- phenylcyclopropoxy)p...)
Affinity DataKd: >3.00E+4nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent