BDBM725403 3-(4-((2,2,2- trifluoroethyl)sulfonamido)phenyl)-5- ((5-(trifluoromethyl)pyridine-2- yl)amino)-1H-pyrazole-4- carboxamide::US20250074891, Compound 153::US12583836, Compound 153

SMILES NC(=O)c1c(-c2ccc(NS(=O)(=O)CC(F)(F)F)cc2)n[nH]c1Nc1ccc(C(F)(F)F)cn1

InChI Key InChIKey=OBYLHHZQRQLIMW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 725403   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725403BDBM725403(3-(4-((2,2,2- trifluoroethyl)sulfonamido)phenyl)-5...)
Affinity DataKd: <10nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725403BDBM725403(3-(4-((2,2,2- trifluoroethyl)sulfonamido)phenyl)-5...)
Affinity DataKd: <10nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725403BDBM725403(3-(4-((2,2,2- trifluoroethyl)sulfonamido)phenyl)-5...)
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725403BDBM725403(3-(4-((2,2,2- trifluoroethyl)sulfonamido)phenyl)-5...)
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725403BDBM725403(3-(4-((2,2,2- trifluoroethyl)sulfonamido)phenyl)-5...)
Affinity DataKd: >3.00E+4nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 725403BDBM725403(3-(4-((2,2,2- trifluoroethyl)sulfonamido)phenyl)-5...)
Affinity DataKd: >3.00E+4nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent