BDBM72549 (E)-3-(dimethylamino)-1-(3-pyrimidin-2-yloxyphenyl)prop-2-en-1-one::(E)-3-(dimethylamino)-1-[3-(2-pyrimidinyloxy)phenyl]-2-propen-1-one::(E)-3-(dimethylamino)-1-[3-(2-pyrimidyloxy)phenyl]prop-2-en-1-one::MLS000721707::SMR000335175::cid_1487580

SMILES CN(C)\C=C\C(=O)c1cccc(Oc2ncccn2)c1

InChI Key InChIKey=BHMKBYVPVJQOMT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72549   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandChemical structure of BindingDB Monomer ID 72549BDBM72549(US20250368667, Compound 99)
Affinity DataIC50: 3.13nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details PCBioAssay